Moguer

The present site of Moguer had been home to many human settlements since antiquity. Nonetheless, the founding of the present municipality is generally dated from the establishment of the Señorío de Moguer ("Seigneury of Moguer") in 1333. The Santa Clara Monastery and a Franciscan convent that later became the Corpus Christi Hospital were founded four years later. From the 1330s, the population grew rapidly, turning Moguer into an important town with a strong, economy based in agriculture, fishing, and trade through the town's river port. Moguer played an important role in the first voyage of Christopher Columbus, with Columbus receiving important support from the abbess of the Santa Clara Monastery, Inés Enríquez, the cleric Martín Sánchez and the landowner Juan Rodríguez Cabezudo. The Niño brothers played an important role in the voyage, including providing the caravel Niña. Upon the returning from the Americas, the first of Columbus's vows was fulfilled by spending a night in the church of the Santa Clara Monastery. Today, Moguer and nearby Palos de la Frontera are home to the lugares colombinos, a tourist route of places associated with undertaking that voyage.

Moguer's river port continued to be an important site for seafaring and trade, exporting the local wines and other merchandise to the Americas, Russia and other European countries.